Improved Conversion Rates in Drug Screening Applications Using Miniaturized Electrochemical Cells with Frit Channels
نویسندگان
چکیده
منابع مشابه
Improved conversion rates in drug screening applications using miniaturized electrochemical cells with frit channels.
This paper reports a novel design of a miniaturized three-electrode electrochemical cell, the purpose of which is aimed at generating drug metabolites with a high conversion efficiency. The working electrode and the counter electrode are placed in two separate channels to isolate the reaction products generated at both electrodes. The novel design includes connecting channels between these two ...
متن کاملMiniaturized biological and electrochemical fuel cells: challenges and applications.
This paper discusses the fundamentals and developments of miniaturized fuel cells, both biological and electrochemical. An overview of microfluidic fuel cells, miniaturized microbial fuel cells, enzymatic biofuel cells, and implanted biofuel cells in an attempt to provide green energy and to power implanted microdevices is provided. Also, the challenges and applications of each type of fuel cel...
متن کاملMiniaturized screening technologies for drug discovery.
Adaptive Profiling (APL) and other biochip companies aim to harness the power of microsystems technology together with advances in chemistry and molecular biology, to become service and technology providers to organizations involved in pharmaceutical research and development. By supplying a unique range of decision-making tools that aid an earlier identification of qualified drug candidates for...
متن کاملFuel cells for electrochemical energy conversion
A fuel cell is essentially a compact electrochemical “factory” that takes fuel as input and produces electricity as output (see fig. 1). Like a factory, a fuel cell will continue to churn out product (electricity) as long as raw material (fuel) is supplied. This is the key difference between a fuel cell and a battery. While both rely on electrochemistry to work their magic, a fuel cell is not c...
متن کاملImproved conversion rates for SNP genotyping of nonmodel organisms
Single nucleotide polymorphisms (SNPs) are the most abundant form of genetic variation and are highly adaptable to large-scale automated genotyping and population genetics studies. For nonmodel organisms, many SNP discovery projects are based on sequencing and assembly of a transcriptome and the calling of sequence variation in contigs. This paper develops a new method for avoiding intron/exon ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2012
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac301888g